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  • Title: [Role of glucocorticoids in the mitochondrial DNA replication].
    Author: Minchenko AG.
    Journal: Probl Endokrinol (Mosk); 1979; 25(5):52-6. PubMed ID: 493255.
    Abstract:
    The liver mitochondrial DNA biosynthesis was found to be enhanced in adrenalectomized rats. Cortisol administration to adrenalectomized rats caused a decrease of the liver mitochondrial DNA biosynthesis. Sedimentation analysis of the mitochondrial DNA in CsCl--EtBr gradient has demonstrated that 3H-thymidine incorporation into the mictochondrial DNA increased mainly in the "open circular" molecules fraction.
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