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  • Title: Morphine, naloxone and kainic acid neurotoxicity.
    Author: McGeer EG, McGeer PL, Vincent SR.
    Journal: Res Commun Chem Pathol Pharmacol; 1979 Aug; 25(2):411-4. PubMed ID: 493724.
    Abstract:
    Local neuronal damage, as indicated by choline acetyltransferase and glutamate decarboxylase activities, elicited by intrastriatal injections of kainic acid was increased by local injection of morphine and decreased by prior injection of naloxone. Peripheral injections of morphine or naloxone had little significant effect although the same trends appeared.
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