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Title: Effect of a vaccination programme on the distribution of rubella antibodies in women of childbearing age. Author: Hambling MH. Journal: Lancet; 1975 May 17; 1(7916):1130-3. PubMed ID: 49484. Abstract: Results of routine rubella hemagglutination-inhibiting antibody tests on 39,005 serum samples showed that 9-5% of women of childbearing age in the Leeds region were seronegative, and a further 9-2% had low antibody titres of 1/8 or 1/16. Since routine rubella vaccination of schoolgirls began in 1970 the frequency of seronegative women in the fifteen to nineteen year age group has fallen by 5-7%. Clinical rubella was confirmed serologically in 140 women, 58 of whom were pregnant. 30 of these pregnancies were terminated, 2 resulted in spontaneous abortions, and 26 proceeded to term. One infant had congenital rubella.[Abstract] [Full Text] [Related] [New Search]