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  • Title: Restoration of gamma globulin production in agammaglobulinemic chickens.
    Author: Cooper MD, Schwartz ML, Good RA.
    Journal: Science; 1966 Jan 28; 151(3709):471-3. PubMed ID: 4955184.
    Abstract:
    Chickens irradiated and bursectomized in the newly hatched period consistently develop agammaglobulinemia and form no circulating antibodies; if the birds are treated immediately after operations by intra-abdominal injection of unirradiated autologous bursa cells, immunoglobulin production, lymphoid germinal centers, and plasma cells are restored; however, the birds fail to produce antibody to specific antigenic challenge.
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