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  • Title: Long-term hypotensive effect of atenolol (ICI 66.082), a new beta-adrenergic blocking agent.
    Author: Hansson L, Karlberg BE, Aberg H, Westerlund A, Jameson S, Henningsen NC.
    Journal: Acta Med Scand; 1976; 199(4):257-61. PubMed ID: 4956.
    Abstract:
    A report is given from an on-going multicenter trial in Sweden, in which 117 hypertensive patients have been treated with a new cardioselective beta-adrenergic blocking agent, atenolol (ICI 66.082, Tenormin) for an average of six months (range 2-21). Statistically significant reductions of BP were observed, recumbent by 29/19 mmHg (p less than 0.0001) and standing by 28/18 mmHg (p less than 0.0001). Few and comparatively mild side-effects were seen.
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