These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Abnormal gangliosides in Tay-Sachs disease, Niemann-Pick's disease, and gargoylism.
    Author: Booth DA, Goodwin H, Cumings JN.
    Journal: J Lipid Res; 1966 May; 7(3):337-40. PubMed ID: 4959256.
    Abstract:
    The molar ratios of N-acetyl neuraminic acid, hexose, hexosamine, and sphingosine have been determined for the abnormal ganglioside in Tay-Sachs disease that was previously detected as a fast-moving band in thin-layer chromatography, and in two abnormal fast-moving bands of gangliosides from the cortex and white matter of the brain in cases of gargoylism and Niemann-Pick's disease. The fastest-moving ganglioside band in these two conditions contains neither hexosamine nor glucose.
    [Abstract] [Full Text] [Related] [New Search]