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Title: Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid. Author: Wold RT, Young FE, Tan EM, Farr RS. Journal: Science; 1968 Aug 23; 161(3843):806-7. PubMed ID: 4969617. Abstract: Antibody to DNA in human serums can be detected by the ammonium sulfate method. This sensitive and specific technique, which measures the primary interaction between DNA and antibody to DNA, is based on the observation that free DNA is soluble in 50-percent saturated ammonium sulfate whereas antibody-bound DNA is insoluble.[Abstract] [Full Text] [Related] [New Search]