These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Enterohepatic circulation of oestriol: a study of the effects of ampicillin on plasma oestriol levels.
    Author: Buchan PC, Klopper A.
    Journal: Br J Obstet Gynaecol; 1979 Sep; 86(9):713-6. PubMed ID: 497143.
    Abstract:
    Plasma total oestriol was measured daily before and during ampicillin therapy in five pregnancy patients and in eight patients, four of whom were receiving ampicillin, for four days following delivery. Ampicillin caused a fall in plasma oestriol of 25 per cent during the first three days of treatment, thereafter the level remained stable with a lower day-to-day variability than in untreated patients. Ampicillin reduced the plasma half life of total oestriol by 60 per cent. This study illustrates how the re-entry of oestriol from the gut leads to irregular fluctuations in plasma oestriol levels and helps to keep up the plasma concentration of the steroid when inflow from the fetoplacental unit is cut off.
    [Abstract] [Full Text] [Related] [New Search]