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  • Title: HLA haplotypes and hayfever: a possible protective role.
    Author: Gwynn CM, Mackintosh P.
    Journal: Clin Allergy; 1979 Sep; 9(5):425-7. PubMed ID: 498485.
    Abstract:
    The HLA haplotype frequencies of European asthmatic children and their immediate families were studied, and a disassociation between haplotype A1-B8 and skin sensitivity to grass pollens was found, suggesting that within this allergic population, possession of the haplotype A1-B8 conferred possible protection against grass pollinosis. There was no association between A1-B8 and clinical asthma or between it and skin sensitivity to the house dust mite.
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