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  • Title: Experimental study on healing of bone fractures using L-dopa.
    Author: Waisman M, Schweppy I.
    Journal: Clin Orthop Relat Res; 1979; (142):244-8. PubMed ID: 498643.
    Abstract:
    Internal fixation with plate and screws was combined with administration of L-Dopa, which presumably operates by stimulating release of growth hormone. The combination induces osteogenesis, callus formation and complete union in the experimental femur osteotomy gap (10-20 mm long). Complete clinical and radiologic union was achieved in dogs treated for 3-6 weeks, thus achieving healing of a bone gap which otherwise would have formed a pseudarthrosis.
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