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  • Title: Sequential study of C 1 q-binding substances and of anti-DNA antibodies in (NZB X NZW)F1 mice: evidence for an acute phase of the lupus disease in 2-month-old mice.
    Author: Fournié GJ, Gayral-Ta Minh M, Haas S, Pourrat JP, Conte JJ.
    Journal: Eur J Immunol; 1979 Aug; 9(8):652-4. PubMed ID: 499331.
    Abstract:
    Longitudinal studies of C 1 q and DNA-binding substances were performed in sera from 38 (NZB X NZW)F1 female mice between days 39 and 150 of life. Results suggest a two-phase evolution of circulating immune complexes and anti-DNA antibodies in young (NZB X NZW)F1 mice and show the existence of an acute phase of the disease during the second month of life of these mice.
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