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  • Title: Beclomethasone dipropionate aerosol in the treatment of asthma in steroid-independent children.
    Author: Chambers WB, Malfitan VA.
    Journal: J Int Med Res; 1979; 7(5):415-22. PubMed ID: 499646.
    Abstract:
    Sixty-eight steroid-independent children, whose asthma was poorly controlled by bronchodilators and other anti-asthmatic drugs, were treated for six weeks with 200 to 400 mcg per day of beclomethasone dipropionate aerosol. Symptoms of wheezing, blockage, and cough, reported by the children in a daily diary, improved in 80% of cases. Use of other anti-asthmatic medications, which the children were free to modify as they wished, decreased. Objective measurements of pulmonary function, VC, FEV1, and FEV%, evaluated by weekly spirometry, also improved in almost 80% of cases. The dosages used here had no effect on early morning plasma cortisol levels and none of the children developed signs of oral candidiasis.
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