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  • Title: A mathematical model of the human body in health, disease, and during treatment.
    Author: Coleman TG.
    Journal: ISA Trans; 1979; 18(3):65-73. PubMed ID: 500352.
    Abstract:
    This paper presents a preliminary description of a mathematical model of the human body and some details of the computer software and hardware used to study the model. The model includes many organ systems of the body and the interplay among systems. In addition to this physiological framework, a variety of diseases and therapeutic measures can be simulated. The model can be used in two different ways. In one mode, hypothetical experiments can be conducted that focus on the underlying physiological mechanisms and the complex interaction among organ systems that are essential to the maintenance of life. In a second mode, clinical encounters can be simulated in which hypothetical patients are seen, diagnosed and treated.
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