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  • Title: Forane increases bleeding in therapeutic suction abortion.
    Author: Dolan WM, Eger EI, Margolis AJ.
    Journal: Anesthesiology; 1972 Jan; 36(1):96-7. PubMed ID: 5006994.
    Abstract:
    The effect of forane, an anesthetic, upon uterine bleeding during therapeutic abortions was examined in 13 women, ranging in age from 19-36 years, who were 8-13 weeks pregnant. 9 received forane-70%nitrous oxide-oxygen maintained at 1.0% or .5%. 4 women received a 1.4% concentration of forane-oxygen. No patients moved during the abortion, performed by the suction technique. The average blood loss was 208 plus or minus 43 ml. In pregnancies of less than 10 weeks, average blood loss was 181 plus or minus 61 ml, while women who were more than 10 weeks pregnant had an average blood loss of 251 plus or minus 55 ml. There was a tendency toward less bleeding (85 plus or minus 13 ml) in the 4 women who received forane without nitrous oxide as compared with the blood loss of the group who used forane with nitrous oxide (262 plus or minus 53 ml). Forane was judged to increase uterine bleeding and was therefore unacceptable as an anesthetic during suction abortions.
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