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  • Title: Isolation and characterization of two major urinary metabolites of 1 -tetrahydrocannabinol.
    Author: Burstein S, Rosenfeld J, Wittstruck T.
    Journal: Science; 1972 Apr 28; 176(4033):422-3. PubMed ID: 5026162.
    Abstract:
    Two of the major metabolites which appear in rabbit urine after the administration of Delta(1)-tetrahydrocannabinol have been isolated and their structures have been tentatively established. The available evidence indicates that they are 7-carboxy-Delta(1)-tetrahydrocannabinols with an additional hydroxyl group on the side chain. The substances occur both free and as conjugates.
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