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  • Title: Arbovirus infections in man in British Columbia.
    Author: Kettyls GD, Verrall VM, Wilton LD, Clapp JB, Clarke DA, Rublee JD.
    Journal: Can Med Assoc J; 1972 Jun 10; 106(11):1175-9. PubMed ID: 5034698.
    Abstract:
    During the summer of 1971, the first laboratory-proved cases of acute encephalitis in man due to any of the known arboviruses occurred in the south-central region of British Columbia. Five human cases of encephalitis with two deaths were diagnosed; three of these patients, including one of the fatalities, were proven in the laboratory to have contracted western equine encephalitis.During 1968 and 1969, a human serum survey undertaken in approximately 2000 life-long residents of the province discovered low levels of hemagglutinin-inhibiting and/or complement-fixing as well as neutralizing antibodies for western equine encephalitis, St. Louis encephalitis, Powassan encephalitis, California encephalitis and Colorado tick fever. Evidence of recent sub-clinical infection was detected in some cases.
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