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  • Title: Some parallelisms n the behavior of pancreatic ribonuclease and chicken lysozyme toward homopolyribonucleotides.
    Author: Preiss JW, Stevenson DA.
    Journal: Biophys J; 1972 Jan; 12(1):80-91. PubMed ID: 5061693.
    Abstract:
    Pancreatic ribonuclease and chicken lysozyme possess gross similarities that are responsible for a common ability to form enormous light-scattering centers in cooperation with homopolyribonucleotides. The light-scattering power of the mixtures is highest when [homopolymer]/[protein] assumes some critical value that is unique for each homopolymer-protein pair. In some respects the scatterers resemble very large antigen-antibody networks. A criterion is established to ascertain the relative abilities of the homopolymers to form the centers with the two proteins. Both see polyinosinic acid (poly-I) as most and polyadenylic acid (poly-A) as least efficient in this respect.
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