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  • Title: Cell surface immunoglobulin. IV. Distribution among thymocytes, bone mrrow cells, and their derived populations.
    Author: Vitetta ES, Bianco C, Nussenzweig V, Uhr JW.
    Journal: J Exp Med; 1972 Jul 01; 136(1):81-93. PubMed ID: 5064226.
    Abstract:
    Thymocytes, bone marrow cells, and their derived T and B cell populations were examined for the presence of Ig by the cell surface radioiodination technique. Both IgM and IgG were identified on bone marrow cells. Thymocytes and T cells had no detectable cell surface Ig. Radiolabeling of mixtures of B cells and thymocytes suggest that the method may detect as little as 250 molecules of Ig per cell. Based on these findings, we suggest that the T cell receptor for antigen is not a conventional tetrameric Ig.
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