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  • Title: The pharmacokinetics of an oral form of carbenicillin in patients with renal failure.
    Author: Bailey RR, Eastwood JB, Vaughan RB.
    Journal: Postgrad Med J; 1972 Jul; 48(561):422-6. PubMed ID: 5069898.
    Abstract:
    An orally active ester of carbenicillin was administered to patients with varying degrees of renal dysfunction. The peak serum levels and serum half-life were found to be increased in patients with renal failure. Urine levels, however, in these patients were above the minimum inhibitory concentration for the majority of urinary tract pathogens.
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