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  • Title: Evaluation of gamma radiation therapy in experimentally induced hemorrhagic pancreatitis in dogs.
    Author: Musa BE, Ferguson HL, Nelson AW, Gillette EL, Lumb WV.
    Journal: Am J Vet Res; 1979 Jul; 40(7):927-30. PubMed ID: 507495.
    Abstract:
    Acute bile-trypsin pancreatitis was induced in two groups of six dogs each. One group was given supportive treatment only; the second group was treated with irradiation of the pancreas (400 rad). A third group of six dogs was irradiated, but pancreatitis was not induced. A 13-fold increase in survival time was observed in the dogs with pancreatitis which had been irradiated. Irradiation alone was found to reduce the volume of pancreatic secretion with a relative increase in trypsin content. Modification of the inflammatory reaction by irradiation and reduction in pancreatic secretion probably account for the therapeutic effect.
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