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  • Title: Increase in the preneoplastic liver lesions by thioacetamide followed by repeated partial hepatectomy.
    Author: Malvaldi G, Pollera M.
    Journal: Boll Soc Ital Biol Sper; 1979 May 30; 55(10):986-9. PubMed ID: 508415.
    Abstract:
    Thioacetamide administration at low dose induces minimal changes in rat liver. Following withdrawal of the drug, the extent of the subsequent cholangiofibrosis and hyperplastic hepatocyte proliferation is strongly enhanced by partial hepatectomies performed monthly on the same animal.
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