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  • Title: Thromboembolism and oral contraceptives.
    Author: Seigel DG.
    Journal: Obstet Gynecol; 1971 Sep; 38(3):478-80. PubMed ID: 5094330.
    Abstract:
    A 1970 study by Fuertes-de la Haba et al. (Obstetrics and Gynecology 36: 597-602) on thromboembolism in Puerto Rican women taking oral contraceptives is criticized. Fuertes-de la Haba et al. interpreted their results as failing to corroborate previous publications indication an increased mortality rate from thromboembolic disorders in women using the oral contraceptive. Siegel indicates that the limitations in the study preclude the possibility of its affecting the understanding of the relationship of oral contraceptives to thromboembolic mortality. The data in the study were inadequate, the number of cases too small to give statistically valid results, and the follow-up of subjects was too faulty to allow accurate inferences.
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