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Title: Endogenous creatinine clearance as a clinical measure of glomerular filtration rate. Author: Bennett WM, Porter GA. Journal: Br Med J; 1971 Oct 09; 4(5779):84-6. PubMed ID: 5097426. Abstract: Endogenous creatinine clearance was assessed by inulin in 91 simultaneous studies in 41 patients and proved an accurate measurement of glomerular filtration rate. For filtration rates <20 ml/min the creatinine clearance may slightly overestimate the glomerular filtration rate. Successive determinations of filtration rate by either method may vary by 20% even though the methods agree with each other. Glomerular filtration rate itself is variable, and in its clinical usage this should be recognized.[Abstract] [Full Text] [Related] [New Search]