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  • Title: Two antibody-producing cell types in four species.
    Author: Avrameas S, Kuhlmann W, Miller HR, Leduc E.
    Journal: Immunology; 1971 Jan; 20(1):85-9. PubMed ID: 5099655.
    Abstract:
    Both differentiating plasma cells and modified lymphocytes (lymphoplasmocytes) synthesize specific humoral antibody in rabbits, rats, mice and guinea-pigs. They do so during both primary and secondary responses, after subcutaneous injection of three enzymic antigens: horse radish peroxidase, glucose oxidase and alkaline phosphatase, administered as soluble or insolubilized proteins or alum precipitated or mixed with Freund's adjuvant.
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