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  • Title: Separation of penicillin G potassium and its degradation products using high-pressure liquid chromatography.
    Author: Vadino WA, Sugita ET, Schnaare RL, Ando HY, Niebergall PJ.
    Journal: J Pharm Sci; 1979 Oct; 68(10):1316-8. PubMed ID: 512869.
    Abstract:
    A high-pressure liquid chromatographic technique was developed for the separation of penicillin G potassium and several of its decomposition products. The method utilized a buffered acetonitrile-phosphate mobile phase on a reversed-phase C18 column. Separation of penicillin G potassium and six degradation products was attained within 25 min.
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