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  • Title: [Clinical experience with cefuroxime in pediatric field (author's transl)].
    Author: Komaki K, Matsueda Y, Masuko J, Fujii R.
    Journal: Jpn J Antibiot; 1979 Nov; 32(11):1122-6. PubMed ID: 513294.
    Abstract:
    Cefuroxime (CXM) was administered to 11 patients with pediatric bacterial infections, and clinical effective results were obtained in all these cases. Causative organisms detected in 5 cases with respiratory tract infection, and with urinary tract infections were all eliminated, and the bacterial count decreased in patients with colitis. As for side effect, 1 case developed eosinophilia, and another case with impaired liver function as underlying disease showed transitory exacerbated examination values. Time-course determinations of blood levels and urinary excretions were performed in 1 case. Fecal levels were determined in 2 cases but could not be detected; inactivation action of CXM was observed from the same fecal filtrate.
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