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  • Title: [Effect of the alkaloid lappaconitine on ion currents through the somatic membrane of Helix pomatia neurons].
    Author: Valeev AE, Dzhakhangirov FN, Magura IS, Sadritdinov FS.
    Journal: Neirofiziologiia; 1979; 11(5):469-74. PubMed ID: 514409.
    Abstract:
    The effect of alkoloid lappaconitine on ionic currents through the somatic membrane of identified neurons of the mollusc Helix pomatia was studied under voltage-clamp conditions. It is shown that 4 mM lappaconitine causes a reversible blocking action on the calcium channels. Concentration exceeding 4 mM causes irreversible changes. Lappaconitine had either an insignificant or no effect on sodium currents.
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