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  • Title: Theoretical of the measurement of choroidal blood flow using a radioactive inert gas clearance technique.
    Author: Strang R, Horton PW, Gillespie FC.
    Journal: Phys Med Biol; 1979 Sep; 24(5):964-75. PubMed ID: 515182.
    Abstract:
    A mathematical model for the diffusion of krypton in ocular tissues and its removal by blood flow has been developed to explain the complex clearance pattern found experimentally in the rabbit--an animal which has predominantly a choroidal circulation. Comparison of theoretical and experimental results has shown that the initial slope of the clearance curve is a measure of choroidal blood flow for values of blood flow over 500 ml/100 g/min. The shape of the curve at later times has been shown to be attributable predominantly to the diffusion of krypton into other ocular tissues.
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