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  • Title: [Isoenzymes of blood serum alkaline phosphatase under experimental cholemia].
    Author: Gromashevskaia LL, Kasatkina MG.
    Journal: Ukr Biokhim Zh (1978); 1979; 51(5):459-62. PubMed ID: 516178.
    Abstract:
    The activity and isoenzymic spectrum of alkaline phosphatase of the blood serum and liver under cholemia caused by deoxycholic acid were compared in healthy animals and in animals with the affected liver. It is shown, that under conditions of the bile acids higher content in the organism due to deoxycholic acid, the total activity increases considerably and there appears an isoenzyme absent in the blood serum of healthy animals. Changes in the activity and isoenzymic spectrum of alkaline phosphatase under experimental cholemia developing against a background of the healthy and affected liver are characterized by certain peculiarities.
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