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  • Title: [Content of lipids and their fractions in erythrocyte membranes of rats with Guerin's carcinoma, A-avitaminosis and the effect of vitamin A in significant doses].
    Author: Liubovich EN, Cherviak MN.
    Journal: Ukr Biokhim Zh (1978); 1979; 51(5):463-6. PubMed ID: 516179.
    Abstract:
    The content of lipids in rat erythrocyte membranes was studied with vitamin A deficiency, Guerin's carcinoma and with administration of significant doses of vitamin A. It is found that vitamin A deficiency decreases the content of phospholipid fractions: phosphatidyl ethanolamine, sphingomyelin, phosphatidyl serine. The content of phosphatidyl choline is unchanged. Under conditions of the experiment the content of cholesterol decreases. This dependence is lost when calculating per 1 g of protein. In erythrocytes of rats with Guerin's carcinoma the content of lipids increases. The character of the results is unchanged when calculating per 1 mg of protein. When administering 200.000 IU of vitamin A the content of the phospholipid and free cholesterol identified fractions lowers significantly.
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