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  • Title: [The eye and oral contraceptives].
    Author: Corcelle L.
    Journal: Annee Ther Clin Ophtalmol; 1971; 22():157-63. PubMed ID: 5163252.
    Abstract:
    After a consideration of the history, general side effects, complications, and implications for the world's population of oral contraceptives, the ophthalmologic complications of the pill are summarized. Severe complications reported include ocular paralysis, papillary edema and thrombosis of the retinal vessels due to thrombosis of the cerebral vessels, particularly of the vertebro-basilar artery. The severe ocular complications fall into 2 categories, neuroophthalmologic and vascular. Neuroophthalmologic complications simulate cerebral tumors: in 4 cases there were 6th cranial nerve paralysis, parietal syndrome, hemianopsia, and papillary edema. Unilateral optic neuritis, usually with papillary edema or retrobulbar neuritis syndrome, occurs in several reports. The vascular complications may be associated with thrombosis of the cerebral vessels or limited to the retinal artery or vein. 150 such cases have been published since 1964. A few reports link thrombosis of other vessels with the pill, such as the central vein or central artery. Minor incidents, e.g., migraine, orbital phlebitis, exophthalmia, catatact, myopia, have been ascribed to the pill. The pill is probably responsible for ocular complications related to thrombosis, migraine, and neuritis, but retrospective studies of a few hundred subjects have not proven the association.
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