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  • Title: [Mechanism of the change in energy and electrolyte metabolism in the respiratory musculature in experimental botulism].
    Author: Morrison VV.
    Journal: Vopr Med Khim; 1979; 25(6):749-52. PubMed ID: 516537.
    Abstract:
    Distinct decrease in concentrations of creatine phosphate and K+ was observed in various respiratory muscles of cat in generalized botulism, accompanied by the syndrom of asphyxia. Content of glycogen and Na+ was unaltered in these cases. In local botulinic paralysis concentrations of creatine phosphate, glycogen and K+ were decreased in the respiratory muscles. Accumulation of Na+ was observed in diaphragm and intercostal muscles. Content of K+ and creatine phosphate was partially restored in respiratory muscles after intraperitoneal administration of guanidine HCl/50 mg/kg of body weight/.
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