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  • Title: [Generalized ceroid histiocytosis in type 5 hyperlipoproteinaemia (author's transl)].
    Author: Höpfel-Kreiner I, Mikuz G, Fill H.
    Journal: Wien Klin Wochenschr; 1979 Nov 23; 91(22):751-5. PubMed ID: 516746.
    Abstract:
    Histochemical, fluorescence and electron microscopic features of histiocytes from the spleen, lymph nodes and liver were investigated in a patient with type 5 hyperlipoproteinaemia with splenomegaly (Fredrickson and Lees, 1965). The pigment stored in histocytes represented ceroid, a product of oxidation and polymerization of unsaturated lipids. The morphological features of ceroid and histogenesis of ceroid histiocytosis are discussed.
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