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  • Title: Juvenile amyotrophic lateral sclerosis. A report of two cases in a single family.
    Author: Myllylä VV, Toivakka E, Ala-Hurula V, Hokkanen E, Emeryk-Szajewska B.
    Journal: Acta Neurol Scand; 1979 Sep; 60(3):170-7. PubMed ID: 517116.
    Abstract:
    This paper presents two juvenile cases of familial amyotrophic lateral sclerosis. They are the first and fourth child in a family with seven children from the eastern part of Finland. All seven children, as well as the parents, were examined by our group. In the first case the disease showed a rather mild course, while in the second a noticeable progression was observed even during a period of 10 months. The patients come from a rural area with a stable population and low immigration, which may favor an enrichment of certain genes and therefore support the possible hereditary basis for the disease.
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