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  • Title: An examination of the role of vitamin E in glucose-6-phosphate dehydrogenase deficiency.
    Author: Newman JG, Newman TB, Bowie LJ, Mendelsohn J.
    Journal: Clin Biochem; 1979 Oct; 12(5):149-51. PubMed ID: 519843.
    Abstract:
    The effect of vitamin E on erythrocyte glutathione stability was studied both in vitro and in vivo on subjects with glucose-6-phosphate dehydrogenase deficiency. The results suggest that lipid membrane peroxidation in glucose-6-phosphate dehydrogenase deficient erythrocytes, which has been postulated to occur under conditions of oxidative stress, does not result in significant depletion of erythrocyte reduced glutathione pools. Vitamin E supplementation in these individuals was shown to have little or no effect on the response of their erythrocytes to oxidative stress.
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