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  • Title: Relationship between blood flow and radiostrontium uptake in the healing bone fracture.
    Author: Schümichen C, Mundriziewski L, Tischler E, Hoffmann G.
    Journal: Eur J Nucl Med; 1979 Dec; 4(6):413-7. PubMed ID: 520354.
    Abstract:
    The healing of a diaphyseal tibia fracture was followed in the rat. Callus formation, blood flow and Sr-85 uptake were assessed by a ratio comparison of the fractured to the contralateral side. No correlation was found between blood flow and Sr-85 deposition in the callus and the adjacent bone of the same extremity. It is concluded that the deposition of a radiopharmaceutical in bone is primarily related to the presence of calcifiable organic bone matrix and only secondarily to the bone formation rate and to variations in the local blood flow.
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