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  • Title: The importance of the terminal hemi-acetal group for the ionophoric properties of nigericin.
    Author: David L, Chapel M, Gandreuil J, Jeminet G, Durand R.
    Journal: Experientia; 1979 Dec 15; 35(12):1562-3. PubMed ID: 520454.
    Abstract:
    Opening of the terminal hemi-acetal in dihydronigericin drastically reduces the ionophoric properties of nigericin and dehydroxymethylnigericin with 6 intact heterocycles. This is shown by 2 complementary methods, first with a liquid membrane electrode system, secondly by testing their ionophoric activities in rat liver mitochondria.
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