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  • Title: Potentiation of levodopa effect by intravenous L-prolyl-L-leucyl-glycine amide in man.
    Author: Barbeau A.
    Journal: Lancet; 1975 Oct 11; 2(7937):683-4. PubMed ID: 52054.
    Abstract:
    L-prolyl-L-leucyl-glycine amide (P.L.G.) has melanocyte-stimulating-hormone-inhibitory hormone (M.I.F.) activity. When injected intravenously as a bolus of 200 mg, it greatly potentiated the effect of an oral levodopa dose upon motor performance objectively measured by a battery of tests. This amelioration in motility was accompanied by improvement in intellectual functioning.
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