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  • Title: [Renaut's bodies and familial neuropathy of the Dejerine-Sottas type. Apropos of 2 anatomo-clinical cases].
    Author: Pasquier B, Couderc P, Pasquier D.
    Journal: Sem Hop; ; 51(31-34):2103-7. PubMed ID: 52195.
    Abstract:
    The authors report the pathological and clinical findings in two cases of familial Dejerine-Sottas neuropathy, including the peripheral nerve lesions of an unusual type producing extensive sub-perineural separation. In one case, there was onion bulb hypertrophy of the schwann layer and definite demyelinisation and above all, endoneural nodular structures known as Renaut bodies. The presence of Renaut bodies has not, to our knowledge, yet been reported in Dejerine-Sotta's disease. It is rare but well known during other neural diseases, which are often familial and in various pathological circumstances, such as syringomylia, diabetes and hypothyroidism. The fibroblastic origin of these structures has been proved. Their possible pathogenic role and their significance are still the object of discussion.
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