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  • Title: [Diuretic evaluation of bumetanide (author's transl)].
    Author: Barrientos Guzmán A, Ortuño de Solo MT.
    Journal: Med Clin (Barc); 1979 Nov 10; 73(8):338-41. PubMed ID: 522529.
    Abstract:
    The intravenous administration of 2 mg bumetanide produces a sudden rise in diuresis in a state of hydropenia as well as in a state of previous aqueous diuresis. This rise, which is not accompanied by changes in the glomerular filtrate and renal plasma flow, seems to be due to a decrease in the reabsorption of chloride and sodium in the Henle's loop and probably to a decrease in the absorption of fluid in the proximal tubule, as is apparently indicated by the fractional excretion of water and sodium and the clearance of phosphorus and uric acid.
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