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  • Title: Combined therapy of L1210 leukemia with Damvar and cytostatics.
    Author: Pujman V, Cernochová S.
    Journal: Neoplasma; 1979; 26(5):521-3. PubMed ID: 522924.
    Abstract:
    Damvar, the delta-(2-amino-6-hydroxy-3,4-dihydro-4-oxo-5-pyrimidinyl) valeric acid, administered alone s. c. or i. p., has no effect on L1210 leukemia. In DBA2 mice with L1210, Damvar administered in combination with 5-fluorouracil, or with 6-mercaptopurine, or with cyclophosphamide, in optimal doses, enhances or intensifies the antileukemic effects of the above cytostatics.
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