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  • Title: Evolution of endemic goiter in the Valea Jiului area after 30 years of iodine prophylaxis.
    Author: Negoescu I, Simescu M, Ciovîrnache M, Vaida E, Georgescu C, Buzică G, Gheorghiţă N, Ghiea D.
    Journal: Endocrinologie; 1979; 17(4):259-63. PubMed ID: 523945.
    Abstract:
    After 30 years of iodine prophylaxis the incidence of goiter in the Valea Jiului area was reassessed. A number of 7,892 pupils aged 7-16 years were examined, of whom goiter was found in 32%. Before iodine prophylaxis started the incidence was 91.8%. The present survey shows that the small-sized goiters markedly prevail over middle-sized ones, while large-sized goiters became extinct. The diffuse to nodular goiter ratio changed by the disappearance of the nodular forms. The neurologic and psychic complications in goiter-bearing children disappeared. Attempts to correlate taste sensitivity to thiocarbamide with goiter failed. Examination of the digito-palmar dermatoglyphics showed a greater incidence of the higher atd angle, with transition forms of sulcus palmaris.
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