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  • Title: Antigenic determinants common to established human B-cell lines, but not shared by human T-cell lines (molt and sommer).
    Author: Takada Y, Takada A, Minowada J.
    Journal: Clin Exp Immunol; 1975 Aug; 21(2):267-77. PubMed ID: 52426.
    Abstract:
    Rabbits were immunized with two kinds of human B-cell lines (SOMMER-B, and RPMI number 1788 cells) to get anti-B-cell sera. Sera were absorbed with human red blood cells, human liver, human brain and human T cells (MOLT-4 and SOMMER-T cells). Cytotoxicity of absorbed sera was not only tested against B cells which were used for immunization but also tested against unrelated B cells, including B35M cells derived from Burkitt lymphoma specimens. Results indicated that established human B cells had antigenic determinants which were shared with allogeneic human B cells, but not shared with non-lymphoid cells or tissues, nor with extablished human T cells.
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