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  • Title: [Effect of duodenal acidification on plasma secretin and pancreatic polypeptide in man (author's transl)].
    Author: Häcki WH, Gyr K, Kayasseh L, Halter F.
    Journal: Z Gastroenterol; 1979 Nov; 17(11):749-52. PubMed ID: 524950.
    Abstract:
    Plasma secretin and pancreatic polypeptide has been measured in 10 normal volunteers before and after intraduodenal acidification. Secretin rose rapidly from 1,4 +/- 0,44 to 11,2 +/- 1,24 pmol/l (+/- SEM). PP also rose significantly from 39,0 +/- 3,0 to 52.3 +/- 5,8 pmol (paired p less than 0.01) but much slower and to a lesser extent than seen after a meal. This supports the conclusion that acid plays no important role in control of postprandial PP release.
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