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  • Title: Remission induction with cytosine arabinoside and L-asparaginase in acute lymphoblastic leukaemia.
    Author: McElwain TJ, Hardisty RM.
    Journal: Br Med J; 1969 Dec 06; 4(5683):596-8. PubMed ID: 5261071.
    Abstract:
    Nine patients with acute lymphoblastic leukaemia in relapse were treated with a course of cytosine arabinoside followed immediately by a course of L-asparaginase. Eight patients achieved complete remission of their disease. This combination of drugs is sufficiently effective to suggest that further trial is needed. It is possible that the combination has a synergistic effect.
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