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  • Title: [Study with serial sectioning of 312 preclinical cancers of the uterine cervix. Indications for selective treatment (author's transl)].
    Author: Bremond A, Dargent D, Frappart L, Beau G.
    Journal: Bull Cancer; 1979; 66(4):455-9. PubMed ID: 526633.
    Abstract:
    The authors have studied by step serial sectioning 312 cervix the most obtained by cold knife conization. They have studied too, the frequency of inadequate resection (i.e. non in sano conization) and clinically occult invasion according to the age of patients. Conization is adequate for the treatment of 70 per cent of women less than 30 years of age. But after 50 it is sufficient in only 22 per cent of the patients. Conization must be performed in most cases of grade III to V cervical smear (according to Papanicolaou's classification). The cervical cone must be studied by serial sectioning (every 500 microns). According to the result of this study the treatment must be selected : conization for in situ carcinoma resected in sano, simple hysterectomy for in situ carcinoma not resected in situ and Wertheim type operation for invasive carcinoma.
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