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  • Title: Translocation of messenger RNA and "accommodation" of fMet-tRNA.
    Author: Thach SS, Thach RE.
    Journal: Proc Natl Acad Sci U S A; 1971 Aug; 68(8):1791-5. PubMed ID: 5288766.
    Abstract:
    Messenger RNA is moved a distance of approximately three nucleotides in the 5' direction relative to the ribosome during the translocation of peptidyl-tRNA from the A to the P site. This movement is catalyzed by G factor and is dependent on the hydrolysis of GTP. In contrast, mRNA is not moved during the f(2)-catalyzed hydrolysis of GTP that is involved in the activation of ribosome-bound fMet-tRNA. This second type of GTP-dependent reaction has been named "Accommodation".
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