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  • Title: [Myocardial protection by perfusion in deep hypothermia (10 degrees C) with or without cardioplegia (author's transl)].
    Author: Mikaeloff P, Amouroux C, Boivin F, Loire R, Vialle C, Guidollet G, Coullet P, Van Haecke P, Bouillot A, Karo G.
    Journal: Nouv Presse Med; 1979 Dec 24; 8(50):4105-7. PubMed ID: 530827.
    Abstract:
    A technique of myocardial protection using a perfusion circuit in deep hypothermia via the ascending aorta or by selective cannulation of the coronaries has been used over a period of 2 years in almost 200 patients undergoing surgery requiring prolonged aortic clamping. It ensures rapid and homogeneous cooling of the myocardium (10-12 degrees C) and meets its reduced oxygen needs. It may be completed by cardioplegia (infusion of potassium chloride or lidocaine using an automatic syringe at a determined level). This simple technique permits a rapid spontaneous return of normal effective cardiac action. No low cardiac output syndromes have been seen since it has been used. Laboratory, histological, biochemical and haemodynamic studies carried out have confirmed its harmless nature.
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