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  • Title: Preparation and biochemical properties of PGH3.
    Author: Smith DR, Weatherly BC, Salmon JA, Ubatuba FB, Gryglewski RJ, Moncada S.
    Journal: Prostaglandins; 1979 Sep; 18(3):423-38. PubMed ID: 531219.
    Abstract:
    PGH3 was biosynthesised from all-cis-5,8,11,14,17-eicosapentaenoic acid (20:5 omega 3) by an acetone-pentane powder of ram seminal vesicles and its structure was confirmed by GLC-MS after its reduction to PGF 3 alpha. PGH3 was transformed by horse platelet microsomes to TXB3, and by aortic microsomes to delta 17-6-keto-PGF 1 alpha. The structures of these compounds were confirmed by GLC-MS.
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