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  • Title: [Diagnosis of primary hyperparathyroidism and differential diagnosis of hypercalcemia].
    Author: Dambacher MA, Fischer JA.
    Journal: Schweiz Med Wochenschr; 1979 Dec 08; 109(47):1897-8. PubMed ID: 531570.
    Abstract:
    The leading symptom in patients with primary hyperparathyroidism (pHPT) is renal lithiasis and not osteopathy. The most abundant circulating forms of parathyroid hormone in pHPT represent COOH-terminal fragments with molecular weights ranging from 4000 to 7000. Radioimmunnoassays making use of antibodies directed to CCOH-terminal parts of human parathyroid hormone are therefore suitable in distinguishing patients with pHPT from control subjects and patients with hypercalcemia unrelated to hyperfunctioning parathyroid glands.
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